Unfolded Protein Response as a Therapeutic Target in Cardiovascular Disease
نویسندگان
چکیده
منابع مشابه
The unfolded protein response genes in human osteoarthritic chondrocytes: PERK emerges as a potential therapeutic target
BACKGROUND The unfolded protein response (UPR) is activated following an endoplasmic reticulum (ER) stress. The aim of this study was to investigate the global expression of UPR genes in human OA chondrocytes in induced (I)-UPR conditions, and to explore the regulation and role of the UPR genes in homeostatic (H)-UPR conditions in human normal and OA chondrocytes. METHODS Gene expression was ...
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ژورنال
عنوان ژورنال: Current Topics in Medicinal Chemistry
سال: 2019
ISSN: 1568-0266
DOI: 10.2174/1568026619666190521093049